Detalhe da pesquisa
1.
Discovery of non-nucleoside oxindole derivatives as potent inhibitors against dengue RNA-dependent RNA polymerase.
Bioorg Chem
; 131: 106277, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36444792
2.
Valbenazine isomers and enantiomer determination by chiral normal phase liquid chromatography.
Chirality
; 35(11): 889-898, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37345319
3.
Development, stability-indicating assessment, and evaluation of influential method conditions using a full factorial design for the determination of Nintedanib esylate-related impurities.
J Sep Sci
; 46(11): e2200770, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36976154
4.
An effective and stability-indicating method development and optimization utilizing the Box-Behnken design for the simultaneous determination of acetaminophen, caffeine, and aspirin in tablet formulation.
Biomed Chromatogr
; 37(4): e5585, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36692333
5.
Development and validation of apalutamide-related substances method in solid dosage forms using HPLC.
Biomed Chromatogr
; 37(4): e5576, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36573285
6.
Estimation of purity of antimicrobial lead compound sulfonamide-anthranilate derivative methyl-ester-toluene-sulfonamide using LC to develop a new drug application.
Biomed Chromatogr
; 37(8): e5646, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37070159
7.
Regioselectivity in inhibition of peptide deformylase from Haemophilus influenzae by 4- vs 5-azaindole hydroxamic acid derivatives: Biochemical, structural and antimicrobial studies.
Bioorg Chem
; 128: 106095, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36049321
8.
Unique liquid chromatography technique for the determination of mirabegron in the presence of polymers; robustness by Design Expert in the light of Quality by Design.
Biomed Chromatogr
; 36(10): e5449, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35831974
9.
Determination of progesterone (steroid drug) in the semi-solid dosage form (vaginal gel) using a stability-indicating method by RP-HPLC/PDA detector.
Biomed Chromatogr
; 36(1): e5246, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34523747
10.
Favipiravir (SARS-CoV-2) degradation impurities: Identification and route of degradation mechanism in the finished solid dosage form using LC/LC-MS method.
Biomed Chromatogr
; 36(6): e5363, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35292997
11.
Development and validation of novel RP-HPLC method for midostaurin determination using analytical quality by design approach from regulatory perspective and determination of major degradation compounds of midostaurin using LC-MS.
Biomed Chromatogr
; 36(12): e5486, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36001450
12.
Molecular Hybrids of Pyazolo[3,4-b]pyridine and Triazole: Design, Synthesis and In Vitro Antibacterial Studies.
Molecules
; 27(21)2022 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36364469
13.
Design, synthesis and biological evaluation of selective hybrid coumarin-thiazolidinedione aldose reductase-II inhibitors as potential antidiabetics.
Bioorg Chem
; 114: 104970, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34120026
14.
Selective inhibition of Helicobacter pylori methionine aminopeptidase by azaindole hydroxamic acid derivatives: Design, synthesis, in vitro biochemical and structural studies.
Bioorg Chem
; 115: 105185, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34329997
15.
A novel LC-MS/MS method for simultaneous estimation of obeticholic acid, glyco-obeticholic acid, tauro-obeticholic acid in human plasma and its application to a pharmacokinetic study.
J Sep Sci
; 44(7): 1307-1323, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33395497
16.
Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agents.
Bioorg Med Chem Lett
; 29(16): 2248-2253, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31239178
17.
Spirocyclic sulfonamides with carbonic anhydrase inhibitory and anti-neuropathic pain activity.
Bioorg Chem
; 92: 103210, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31473472
18.
A diversity oriented synthesis of natural product inspired molecular libraries.
Org Biomol Chem
; 15(43): 9108-9120, 2017 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29048087
19.
Boronic acid-containing CXCR1/2 antagonists: Optimization of metabolic stability, in vivo evaluation, and a proposed receptor binding model.
Bioorg Med Chem Lett
; 25(11): 2280-4, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25933594
20.
Dual active pyrimidine-based carbocyclic nucleoside derivatives: synthesis, and in silico and in vitro anti-diabetic and anti-microbial studies.
RSC Adv
; 14(14): 9559-9569, 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38516166